Effectiveness of Transcranial Direct Current Stimulation in Chronic Pain Related to Lumbar Spinal Stenosis
Unknown statusNot applicableNCT03958526
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Transcranial Direct Current Stimulation (tDCS) is a promising non-invasive brain stimulation technique in chronic pain. There is no study investigating the effectiveness of tDCS in radiating chronic lower extremity pain related to lumbar spinal stenosis (LSS). The aim of this study is to investigate the effects of tDCS on pain, walking capacity, functional status and quality of life in patients with chronic pain related to LSS. 32 patients diagnosed with chronic pain related to LSS will be enrolled in this prospective, randomized, double blind, placebo-controlled study according to inclusion/exclusion criteria. Patients in active group will receive 10 sessions of anodal tDCS delivered over primary motor cortex (M1) with a constant current of 2 miliAmpers for 20 minutes. Patients will be evaluated at baseline, on day 1, 5 and 10 (after the session) and 5 days, 1 month and 3 months after treatment.
Study details
- Official title
- Effectiveness of Transcranial Direct Current Stimulation in Chronic Pain Related to Lumbar Spinal Stenosis
- Conditions
- Lumbar Spinal Stenosis
- Interventions
- Sponsor
- Istanbul University
- Start date
- 2019-04-01
- Primary completion
- 2019-09-30
- Sex
- All
- Age range
- from 45 Years
- Results posted
- No results posted in this snapshot
- Countries
- Turkey (Türkiye)
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Magnetic resonance imaging evidence of narrowing of the central canal, lateral recess, and/or foramen. * Persistent leg pain for at least 3 months * An average pain intensity score (during walking) of at least 4 out of 10 on the Visual Analog Scale at screening and randomisation * Persistent neurogenic claudication for at least 3 months * stable pharmacological treatment for pain and sleep disorders for at least 1 month before the study and throughout the trial * If present, coexisting low back pain intensity should be less than leg pain intensity. Exclusion Criteria: * Patients with other neurological or psychiatric disorders including ongoing major depression (Beck Depression Score\>14) * Uncontrolled/unstable endocrinologic, cardiovascular, pulmonary, hematologic, hepatic, renal disease * Inflammatory diseases, cancer * Severe hip and/or knee osteoarthritis that affects Treadmill Walking Test * Absolute/relative contraindications of tDCS (past head trauma resulting with loss of consciousness, epilepsy, past neurosurgical intervention, intracranial hypertension, implanted devices, migraine, chronic-severe headache episodes, a history of side effects with non-invasive brain stimulation techniques, skin diseases, pregnancy)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03958526