Acute Effects of Alcohol Use on Chronic Orofacial Pain
CompletedNot applicableNCT04019093
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Self-medication of pain with alcohol is a common, yet risky, behavior among individuals with chronic orofacial pain. Chronic pain status may affect the degree to which alcohol use relieves pain, but the independent contributions of pain chronification and alcohol-related expectations and conditioning have not been previously studied. This project addresses this gap in knowledge and will inform further research and clinical/translational efforts for reducing risk associated with these behaviors.
Study details
- Official title
- Acute Effects of Alcohol Use on Chronic Orofacial Pain
- Conditions
- Interventions
- Drug: Ethanol
- Other: Placebo
- Sponsor
- University of Florida
- Collaborators
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Start date
- 2019-11-05
- Primary completion
- 2022-04-30
- Sex
- All
- Age range
- from 21 Years to 45 Years
- Healthy volunteers
- true
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Positive diagnosis of jaw pain, including temporomandibular joint and muscle disorder (TMD) (jaw pain group only) * Consume at least 1 drink/month over the past 6 months Exclusion Criteria: * History of chronic pain other than jaw pain or TMD * Current use of opioids * Current major depression * History of any psychotic disorder * Undercontrolled hypertension or diabetes * History of neurologic disease * History of serious medical illness * History of drug or alcohol dependence, including nicotine, or a pattern of hazardous alcohol use
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04019093