Dexmedetomidine-Ketamine Infusion in Breast Surgeries
CompletedPhase 4NCT04048226
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
* This is a prospective randomized double blind controlled study. * Female patients undergoing radical mastectomy will be included in this study where they will be randomly allocated into; - Control group in which patients will receive continuous infusion of normal saline. Dexmedetomidine-Ketamine group in which patients will receive continuous infusion of ketamine and dexmedetomidine. The intraoperative and postoperative opioid consumption will be measured. Also, the postoperative pain score and the incidence of chronic pain will be assessed.
Study details
- Official title
- The Effect of Intraoperative Dexmedetomidine-Ketamine Infusion on the Patients Undergoing Radical Mastectomy: Randomized Controlled Study
- Conditions
- Total Intravenous Anesthesia
- Interventions
- Drug: Placebos
- Drug: Dexmedetomidine +Ketamine
- Sponsor
- Tanta University
- Start date
- 2019-09-01
- Primary completion
- 2024-03-20
- Sex
- Female
- Age range
- from 50 Years to 70 Years
- Results posted
- No results posted in this snapshot
- Countries
- Egypt
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Female patients aged 50-70 years, ASA class I-III, and presented for elective radical mastectomy. Exclusion Criteria: * Patients refused to participate. * Patients with known or suspected or known allergy to the used medication. * Patients with preoperative chronic pain, * Patients received preoperative opioids or gabapentoids. * Patients with major cardiac, renal, respiratory, or hepatic disease. * Uncooperative patients. * Obese patients with BMI \>36
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04048226