Effect of Metformin on Chronic Pain After Thoracic Surgery in Diabetic Patients
Unknown statusNCT04089813
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Metformin has been found to have more and more functions as a commonly used hypoglycemic drug in clinic. It has been found that metformin has anti-inflammatory, anti-tumor and lipid metabolism regulating effects. Basic studies have shown that metformin as an adjuvant drug combined with gabapentin and tramadol is safe and effective in patients with neuropathic pain. Postoperative chronic pain as a common complication has seriously affected the quality of life and mood of patients after surgery.Some studies have shown that chronic pain after partial operation manifests as neuropathic pain. The effect of metformin on chronic pain after thoracic surgery in patients with diabetes mellitus was observed in this experiment, which was compared with patients taking insulin to control blood sugar.
Study details
- Official title
- Effect of Metformin on Chronic Pain After Thoracic Surgery in Diabetic Patients
- Conditions
- Postoperative Chronic Pain
- Interventions
- Drug: Metformin
- Sponsor
- Xuzhou Medical University
- Start date
- 2019-09-10
- Primary completion
- 2019-12-09
- Sex
- All
- Age range
- from 18 Years to 70 Years
- Results posted
- No results posted in this snapshot
- Countries
- China
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Aged between 18 and 70 2. Diabetes history. Use metformin or insulin to control blood sugar 3. The type of operation is selective thoracoscopic lobectomy. Exclusion Criteria: 1. Newly diagnosed diabetic patients at admission 2. Complication of severe cardiopulmonary diseases 3. Refuse to participate in this experiment 4. Participate in other trials 5. Patients with diabetic complications (including diabetic nephropathy, peripheral neuropathy, etc.)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04089813