BRAIN, Symptoms, and Physical Activity in COPD
CompletedNCT04291131
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Persons with COPD have both chronic musculoskeletal pain and dyspnea that require accurate diagnosis and treatment, ultimately to optimize functional status. The investigators propose to use advanced neuroimaging techniques to understand central mechanisms of chronic pain, dyspnea, and physical activity promotion in COPD. The investigators' novel proposal to correlate subjective symptoms (chronic pain and dyspnea) with an objective central biomarker (resting state functional connectivity) and examine their changes in response to a non-pharmacological, non-addictive physical activity intervention will personalize the care of Veterans with COPD.
Study details
- Official title
- Effects of Chronic Pain, Dyspnea, and Physical Activity Promotion on Functional Connectivity of the Brain in COPD
- Conditions
- Sponsor
- VA Office of Research and Development
- Start date
- 2020-07-01
- Primary completion
- 2024-06-30
- Sex
- Male
- Age range
- from 40 Years
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Greater than or equal to 40 years of age * Clinical diagnosis of COPD defined as either a ratio of FEV1 to forced vital capacity \< 0.70 or chest CT evidence of emphysema or prior documentation of FEV1/FVC ratio of \< 0.7 and clinical evidence of COPD (defined as 10 pack-year cigarette smoking history, dyspnea, or on bronchodilators) * Will participate in a physical activity intervention or exercise program * Competent to provide informed consent * Willingness to make return visits and be available by telephone for duration of study Exclusion Criteria: * Female sex * Claustrophobia * History of seizures * Known brain lesion * Current diagnosis of bipolar disorder, schizophrenia, or psychotic disorder * Cognitive disorder such as dementia * Known metal in body including: * shrapnel * surgical medical clips * implants * pacemakers * metal-based tattoos
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04291131