Impact of a Yoga Intervention on Pain and Multiomics in Participants With IBS
CompletedNot applicableNCT04315714
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this research study is to see if a six-week yoga program delivered online/virtually via Zoom, reduces abdominal pain in people with irritable bowel syndrome (IBS). This study also looks at whether the yoga program changes the composition of microorganisms in the gut and their metabolites, and compares the program in people with IBS versus healthy people (also known as "healthy controls" or "HC"). People in this study are randomized (like flipping a coin) to one of two conditions: half of the people attend the online/virtual private yoga program delivered via Zoom for the first six-weeks, and half of the people wait for six-weeks and then attend the online/virtual private yoga program for six-weeks. The hypothesis of this study is that the practice of yoga induces shifts in the gut microbiota and microbial-derived metabolites, which will correlate with diminished abdominal pain.
Study details
- Official title
- Impact of a Yoga Intervention on Chronic Abdominal Pain, and Associations With the Metagenome and Metabolome in Participants With IBS
- Conditions
- Interventions
- Other: Yoga Program
- Sponsor
- University of Maryland, Baltimore
- Collaborators
- National Institute of Nursing Research (NINR)
- Start date
- 2021-03-04
- Primary completion
- 2021-08-24
- Sex
- All
- Age range
- from 18 Years to 55 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Ability to read/write in English * Access to smartphone/computer/email; Internet and camera access for online/virtual yoga sessions via Zoom * Physical ability to engage in twice weekly yoga for 6 weeks (60 minutes each session), with physical clearance provided by current healthcare provider * Diagnosis of IBS and IBS subtype (for cases), with documentation provided by current healthcare provider * Self-report average, abdominal pain over past 7 days ≥ 3 (for cases: on 0-10 scale) * Willingness to participate in all study procedures Exclusion Criteria: * Regular yoga practice (past 3 months) * Recent antibiotic use (past 3 months) * Consumption of a strict vegan/vegetarian diet * Plan to initiate prebiotic/synbiotic/probiotic use during study period * Any medical condition (cardiac, pulmonary, neurological, musculoskeletal, immunological etc.) that would preclude engagement in the yoga intervention * Any organic gastrointestinal condition (inflammatory bowel disease: Crohn's disease, Ulcerative Colitis, active H. pylori infection, etc.) * Severe comorbid pain or psychiatric condition requiring recent hospitalization * Pregnancy, or plans to become pregnant during study period * Unwilling to participate in study procedures
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04315714