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Brain Effects of Opiate Agonist and Antagonist

CompletedPhase 4NCT04342130
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

This study will look at the short-term effect of morphine on brain response to food.

Study details

Official title
Brain Effects of Opiate Agonist and Antagonist
Interventions
Sponsor
University of Rochester
Start date
2018-04-27
Primary completion
2019-04-16
Sex
All
Age range
from 18 Years to 65 Years
Healthy volunteers
true
Results posted
Yes, on ClinicalTrials.gov
Countries
United States
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Healthy participants * Patients in pain: suffering from persistent pain more days than not, 3/10 in intensity on a numerical rating scale, for at least 6 weeks or more. Exclusion Criteria: * Any DSM diagnosis * diabetes * food allergies * lactose intolerance * participants seeking to quit smoking or to lose weight * participants on any psychotropic medication including opiate based analgesics (e.g. oxycodone, methadone, suboxone) * pregnant or nursing women * pacemaker or other implanted electrical devices * Participants with a past history of head trauma or seizures * Any past history of illegal drug or alcohol misuse * Participants who cannot undergo an MRI scan.

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04342130