PET/MRI in the Diagnosis of Pediatric Chronic Pain
CompletedPhase 1NCT04435821
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
\[18F\]FTC-146 is a sigma-1 receptor detector and is an experimental radiotracer. Several studies have implicated involvement of sigma-1 receptors in generation and perpetuation of chronic pain conditions, while others are investigating anti sigma-1 receptor drugs for treatment of chronic pain. Using \[18F\]-FTC-146 and PET/MRI, we hope to learn what is the best approach to identify the source of pain generation and characterize the disease in pediatric patients with chronic pain.
Study details
- Official title
- Use of PET/MRI in the Diagnosis of Pediatric Chronic Pain
- Conditions
- Chronic Pain
- Pediatric Disorder
- Neuropathic Pain
- Nociceptive Pain
- Interventions
- Drug: [18F]FTC-146
- Sponsor
- Stanford University
- Collaborators
- GE Healthcare
- Start date
- 2020-11-19
- Primary completion
- 2022-12-31
- Sex
- All
- Age range
- from 11 Years to 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * 11-18 years old. * Chronic pain (nociceptive, neuropathic or mixed pain) lasting at least 2 months. * Pain level of at least 4/10 on a 0-10 Comparative Pain Scale (reported at time of screening). * Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative test result from the Covid test within 72 hours of the scan. Exclusion Criteria: * MRI incompatible * Pregnant or nursing * Non-English speaker * Claustrophobic
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04435821