The Effect of Danzhu Fuyuan Granule as Adjunctive Therapy for Chronic Stable Angina, Vascular Dementia and Idiopathic Membranous Nephropathy: A Bayesian Basket Trial

Eligibility Criteria for Chronic Stable Angina group Inclusion criteria for Chronic Stable Angina group 1. Patient must be between the ages of 40 and 70 years 2. Evidence of coronary artery disease that consists of a well-documented medical history (over 3 months prior to the enrollment) of myocardial infarction or significant coronary artery disease with noninvasive or angiographic confirmation. 3. Patient must match the diagnostic criteria for chronic stable angina set by Chinese Medical Association; 4. The number of angina pectoris attacked in the past 3 months was more than 2 times per week 5. Class I or Class II, Grading of Angina Pectoris by the Canadian Cardiovascular Society Classification System 6. Patients who met the clinical diagnostic criteria for Syndrome of intermingled phlegm and blood stasis with chronic stable angina; 7. The results of Treadmill Exercise Test were positive; 8. All other Traditional Chinese Medicine interventions (including decoction, granule, proprietary Chinese medicine, acupuncture, etc.) should be stopped for 2 weeks or more; 9. They signed the consent form voluntarily and agreed to participate in the research. Exclusion criteria for Chronic Stable Angina group 1. patients who are diagnosed with acute coronary syndrome (including acute myocardial infarction or unstable angina pectoris) occurred within 2 months before enrollment, or had undergone revascularization within 3 months before enrollment, or planned to undergo revascularization during the study period; 2. Patients who are unable to complete Treadmill Exercise Test for various reasons, including absolute and relative contraindications; 3. Severe primary diseases such as respiratory, blood system or malignant tumor, or known renal insufficiency (serum creatinine (CR) \> 221 umol /L in male, or 177 umol / L in female); 4. Patients with epilepsy who had bleeding tendency, history of cerebral hemorrhage, or needed anticonvulsant therapy; 5. Patients with active liver disease, or accompanied with unexplained continuous increase of serum transaminase, or the detection value of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) is more than twice the upper limit of normal reference value; 6. Pregnancy or lactation; 7. patients can't stopped taking long-acting nitrates during the clinical trial; 8. undergoing other clinical trials; 9. There was a history of alcoholism or drug dependence in the past two years; 10. Other situations that the research phys…