Combining Non-invasive Brain Stimulation and Exercise to Treat Low Back Pain

CompletedNot applicableNCT04555278

View the official record on ClinicalTrials.gov

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Brief summary (from the registry)

The aim of this study is to evaluate the efficacy of repetitive transcranial magnetic stimulation alone and in combination with motor control exercises on pain and disability for patients with chronic non-specific low back pain.

Study details

Official title: Repetitive Transcranial Magnetic Stimulation Alone and in Combination With Motor Control Exercise for the Treatment of Patients With Chronic Non-specific Low Back Pain (ExTraStim Trial): Study Protocol for a Randomized Controlled Trial
Conditions: Chronic Low-back Pain
Interventions: Device: Active rTMS
Device: Sham rTMS
Other: Motor Control Exercises
Sponsor: Hugo Massé-Alarie
Collaborators: Pfizer; The Canadian Pain Society; Canadian Institutes of Health Research (CIHR)
Organization: Laval University
Start date: 2020-09-25
Primary completion: 2024-03-01
Sex: All
Age range: from 18 Years
Results posted: No results posted in this snapshot
Countries: Canada
Total sites listed: 1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)

Inclusion Criteria: * chronic low back pain, defined as "pain in the low back area with or without leg pain above the knee limiting activities or daily routine which has been present for more than 3 months"; * a minimal average pain intensity of 3 out of 10 during the preceding week on a pain numerical rating scale; * a minimal score of 10 points on the Oswestry disability index (ODI). Exclusion Criteria: * specific spinal pathology (fracture, tumor, radiculopathy, spinal infection, etc.); * a history of back surgery; * a major orthopedic, neurological, cardiovascular or psychiatric illness; * low back pain is not the main pain complaint; * currently using an exercise program to treat their LBP; * presenting with any specific TMS/rTMS-related exclusion criteria such as previous seizure/convulsion, cochlear implant, specific medication and pregnancy; * previous use of repetitive transcranial magnetic stimulation.

Canadian sites (1)

Facility	City	Province
CIRRIS (Centre Interdisciplinaire de Recherche en Réadaptation et Intégration Sociale)	Québec	Quebec

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04555278