Effect of Tramadol Versus Morphine on PD1 and PD1-ligand in Patients With Chronic Cancer Pain
Unknown statusPhase 2, Phase 3NCT04589494
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
this work is looking for comparison between the effect of tramadol versus morphine on PD1 and PD1-ligand in patients with chronic cancer pain
Study details
- Official title
- Comparison Between the Effect of Tramadol Versus Morphine on PD1 and PD1-ligand in Patients With Chronic Cancer Pain
- Conditions
- Interventions
- Drug: Tramadol Hydrochloride
- Sponsor
- Assiut University
- Start date
- 2020-04-16
- Primary completion
- 2021-02
- Sex
- All
- Age range
- from 18 Years to 70 Years
- Results posted
- No results posted in this snapshot
- Countries
- Egypt
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * patients with cancer pain of varying etiology, * documented metastatic cancer, currently on step I WHO ladder and whose pain necessitates a shift to step II, * those who have never received radiotherapy, chemotherapy, or immunosuppressive drugs, -- and in good general and nutritional condition and without infectious diseases at the time of investigation. Exclusion Criteria: * abnormal hepatic, renal, and pulmonary function, gastrointestinal pathology, and * those with cerebral metastases and/or psychological disorders, * patients with contraindication to morphine or tramadol according to their respective data sheets, and * patients who could not complete the diary information correctly.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04589494