Cervical Plexus Block (CPB) in Whiplash Associated Disorder (WAD)
CompletedNCT04622020
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Whiplash is the most common injury associated with motor vehicle accidents and a major cause of disability and litigation. An acute whiplash injury follows sudden or excessive hyperextension, hyper flexion, or rotation of the neck affecting the soft tissues. It typically results from rear-end or side-impact motor vehicle collisions. Patients commonly present with pain and stiffness in the neck, headache, and upper backache. Chronic whiplash syndrome is characterized by symptoms of neck pain that persist for more than 3 months (1, 2). With over half a million people making whiplash injury claims per annum in the UK, it has a major impact on the healthcare and legal systems and also the economy. Over 40% of patients with whiplash injury report chronic neck pain and this is often refractory to conservative management (pain relief medications, physiotherapy). Current treatment involves burning the small nerves that supply the joints (facet joints) in the neck. Although they provide pain relief that can last 6-9 months, the nerves re-grow and the treatment has to be repeated. This treatment is a complex procedure that requires extensive training and has the potential to cause serious harm. There is new evidence to show that the pain in whiplash injury could be due to an impaired function of the neck muscles arising from whiplash trauma. Current treatment for this condition is injection of numbing medicine or steroids directly into the muscle. Although this treatment is safer than burning the facet nerves, it provides short-term relief. The investigators have shown that a novel treatment targeting the nerves that supply the muscles in the neck can provide durable relief in patients with chronic neck pain. The medication is injected into a specific area (plane) in the neck of the patient and is called cervical plexus block (CPB). The investigators currently offer CBP treatment as a standard treatment in the management of patients with chronic neck pain arising from whiplas…
Study details
- Official title
- Effectiveness of Ultrasound Guided Intermediate Cervical Plexus Block (iCPB) in Patients With Refractory Chronic Neck Pain From Whiplash Associated Disorder (WAD): an Observational Study
- Conditions
- Whiplash Associated Disorder
- Interventions
- Procedure: Cervical Plexus Block with Local Anaesthesia
- Procedure: Cervical Plexus Block with Depot Steroids
- Sponsor
- University Hospitals, Leicester
- Start date
- 2020-06-26
- Primary completion
- 2022-08-20
- Sex
- All
- Age range
- from 18 Years to 90 Years
- Results posted
- No results posted in this snapshot
- Countries
- United Kingdom
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. All patients aged over 18 years and under 90 years willing to consent 2. History of whiplash injury 3. Chronic neck pain for above 3 months 4. Moderate to severe pain in the neck: Baseline NRS \>4 (worst pain the last 24 hours) Exclusion Criteria: 1. Lack of consent, including from those patients who lack mental capacity to give informed consent. 2. Past History of chronic neck pain that was present before suffering a whiplash injury 3. Patients with known history of drug allergy to depomedrone 4. Patients with infection at injection site at on day of treatment 5. Patients aged under 18 years or over 90 years 6. Unwilling to provide consent
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04622020