Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA
CompletedNot applicableNCT04814992
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
A significant number of patients develop chronic post-surgical pain (CPSP) following knee replacement surgery. Proposed is the testing of a novel computer-assisted behavioral intervention integrating motivational interviewing in the 4 weeks prior to surgery to address the risk factors for CPSP, with the expectation that severity of post-op pain and the incidence of CPSP will be reduced.
Study details
- Official title
- Pre-op CBT to Reduce the Risk for Development of Chronic Post-surgical Pain in Patients Undergoing Total Knee Arthroplasty
- Conditions
- Interventions
- Behavioral: Computer-Assisted Preoperative CBT Intervention (PAINTrainer)
- Sponsor
- University of Pennsylvania
- Start date
- 2020-10-01
- Primary completion
- 2023-12-31
- Sex
- All
- Age range
- from 22 Years
- Healthy volunteers
- true
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 4
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Males and females, age \> 21 years 2. Chronic non-malignant pain of at least 3 months duration 3. Morphine equivalent daily dose (MEDD) \> 40 milligrams for at least 3 months 4. Able to enroll at least 4 weeks prior to planned surgery 5. Able to speak, read and comprehend in English at the 6th grade or higher proficiency Exclusion Criteria: 1. Pain of malignant origin 2. Current or past history of opioid use disorder (including those on medication-assisted therapy) 3. Revision of TKA 4. Comorbid CNS disease such as dementia, HIV, psychosis, poorly controlled bipolar disorder or any condition interfering with informed consent
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04814992