Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp
CompletedNot applicableNCT04983524
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Propolis is a resinous product of honeybees. Propolis is said to be effective against resistant microorganisms inside the root canal compared to the gold standard medication known as calcium hydroxide. The clinical trial tests the effect of propolis versus calcium hydroxide on pain in patients with necrotic teeth.
Study details
- Official title
- Evaluation of the Effect of Propolis Versus Calcium Hydroxide, Intracanal Medicaments on Post-Operative Pain in Patients With Necrotic Pulp (A Randomized Clinical Trial)
- Conditions
- Post-Operative Pain, Chronic
- Necrotic Pulp
- Interventions
- Dietary supplement: propolis
- Drug: Calcium Hydroxide
- Sponsor
- Cairo University
- Start date
- 2015-10
- Primary completion
- 2018-05
- Sex
- All
- Age range
- from 20 Years to 40 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Total sites listed
- 0
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * • Asymptomatic patients with age range 20 - 40 years * Necrotic, single canal maxillary and mandibular teeth with periapical infection presented as radiolucency or widening in the periodontal membrane space. * Medically - free of any systemic disease * Teeth with complete root formation Exclusion Criteria: * • Pregnant or lactating females * Teeth with vital pulps, internal or external resorption or anatomic abnormalities * Teeth with cracks, curvatures, root caries and calcified canals * Double or triple-rooted teeth * Patients with facial swelling, acute pulpal or periapical lesion * Teeth that are not indicated for endodontic treatment: Bad oral hygiene, mobile or recessed * Previously endodontically-treated teeth
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04983524