Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis
RecruitingNot applicableNCT04996628
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Abdominal pain in chronic pancreatitis (CP) affects up to 90% of patients during the course of their disease, and response to currently available therapies is suboptimal and unpredictable. The proposed clinical trial will evaluate the predictive capability of Pancreatic Quantitative Sensory Testing (P-QST) - a novel assessment of neurosensory phenotyping- for improvement in pain in patients with CP who are undergoing medically-indicated invasive treatment with endoscopic therapy or surgery.
Study details
- Official title
- Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis
- Conditions
- Interventions
- Diagnostic test: Quantitative Sensory Test 1
- Diagnostic test: Quantitative Sensory Test 2
- Diagnostic test: Quantitative Sensory Test 3
- Sponsor
- University of Pittsburgh
- Collaborators
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Start date
- 2022-01-04
- Primary completion
- 2027-06-30
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 3
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Adult patients ≥ 18 years of age with definite CP undergoing decompressive invasive treatments (endoscopic therapy or surgery) to relieve main pancreatic duct obstruction due to stones and/or stricture for management of pain. * Endoscopic therapy: Endoscopic Retrograde Cholangiopancreatography (ERCP) with pancreatic duct stone removal, stent placement, and/or stricture dilation, ± intraductal lithotripsy or Extracorporeal Shock Wave Lithotripsy (ESWL). * Surgery: drainage procedures (Frey and Puestow operations) Exclusion Criteria: * Patients with chronic pain from conditions other than CP * Patients \< 18 years of age * Patients who have had endoscopic therapy within the past 12 months * Patients who have undergone prior pancreatic surgery * Patients who have resective surgical procedure planned (eg. Whipple procedure, Total Pancreatectomy) * Patients with peripheral sensory deficits * Patients with known pregnancy at the time of study screening\*\* * Note: Women who become pregnant during the course of the study can no longer participate in P-QST testing.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT04996628