Effects of Transcutaneous Vagus Nerve Stimulation in Chronic Pain Patients and Healthy Controls
Unknown statusNot applicableNCT05007743
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The tVNS-PP trial investigates the effects of transcutaneous vagus nerve stimulation (tVNS) on autonomic functions, immune responses, and disease severity in chronic pain and restless legs syndrome (RLS) patients as compared to healthy controls.
Study details
- Official title
- Randomized Trial of Effects of Transcutaneous Vagus Nerve Stimulation in Chronic Pain Patients and Healthy Controls
- Conditions
- Restless Legs Syndrome
- Chronic Pain
- Interventions
- Device: Transcutaneous vagus nerve stimulation
- Sponsor
- University Medical Center Goettingen
- Start date
- 2019-07-21
- Primary completion
- 2023-08
- Sex
- All
- Age range
- from 18 Years to 80 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Germany
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion criteria: * Male and female participants between 18 and 80 years old * Written informed consent Exclusion criteria: * Age younger than 18 years or older than 80 years * Participants with somatic or mental comorbidities, especially malignant tumor diseases, cardiac insufficiencies \> NYHA II, severe depressive episodes, psychosis or dementia * Pregnancy or breast feeding * Addictions to alcohol, medications or drugs (except tobacco) * An existing legal guardianship * Participation in another scientific study within the previous eight weeks before enrollment * Restless Legs Syndrome patients with one of the following secondary predispositions: iron deficiency, polyneuropathy, prolapsed disk, spinal stenosis or chronic obstructive pulmonary disease
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05007743