Restricting Blood Flow in Improving Muscle Strength in Patients With Hemophilic Arthropathy
CompletedNot applicableNCT05039008
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Background. The main physical sequela of patients with hemophilia is the development of a progressive, degenerative intra-articular lesion, known as hemophilic arthropathy). This sequela is manifested by chronic pain, limited range of motion, axial abnormalities, and periarticular muscle atrophy. Objective. To assess the safety and effectiveness of an intervention through blood flow restriction, regarding the frequency of bleeding and the improvement in the perception of muscle activation and strength, functionality, joint pain, joint status and the perception of quality of life in patients with hemophilic arthropathy. knee and ankle. Study design. Randomized, multicenter, single-blind clinical study. Method. 20patients with hemophilia A and B will be recruited in this study. Patients will be recruited in 3 regions of Spain. The dependent variables will be: bleeding frequency (self-registration), pain (measured with the visual analog scale), joint status (Hemophilia Joint Health Score scale), strength (dynamometer) and range of motion (goniometer). Three evaluations will be carried out: pre-treatment, post-treatment and after a follow-up period of 4 weeks. Expected results. Observe the safety of blood flow restriction in hemophilia patients. To analyze the efficacy of blood flow restriction in improving muscle strength, joint pain, range of motion, and joint damage in patients with hemophilic knee and ankle arthropathy.
Study details
- Official title
- Effectiveness of Physiotherapy Intervention by Restricting Blood Flow in Improving Muscle Strength in Patients With Hemophilic Arthropathy. Randomized Multicenter Clinical Study.
- Conditions
- Hemophilia
- Interventions
- Other: Blood flow restriction
- Sponsor
- Investigación en Hemofilia y Fisioterapia
- Start date
- 2023-09-06
- Primary completion
- 2023-11-14
- Sex
- Male
- Age range
- from 18 Years to 65 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Spain
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Patients diagnosed with hemophilia A and B * Patients with a medical diagnosis of hemophilic ankle and knee arthropathy * People over 18 years of age * Patients on prophylactic or on-demand treatment regimen with FVIII / FIX concentrates Exclusion Criteria: * Patients with neurological or cognitive disorders that impede understanding of the test. * Pain free patients * Amputees, epileptics or patients with severe vision problems * Patients who are receiving Physiotherapy treatment at the time of the study * Patients who have not signed the informed consent document
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05039008