The Effectiveness of Pain Neuroscience Education in At-risk Patients Following Surgery for Lumbar Radiculopathy
TerminatedNot applicableNCT05047679
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This study aims to assess the effectiveness of perioperative pain neuroscience education (PPNE) in patients who are at risk for unfavorable outcome following surgery for lumbar radiculopathy. Although most of these surgeries are successful, 23-28% of patients report chronic pain and disability following surgery. Many preoperative factors are associated with an unfavorable surgical outcome, including maladaptive cognitive and emotional factors. Yet, current preoperative education, which focuses on anatomy and biomechanics of the lumbar spine, is ineffective in changing those maladaptive factors. PPNE was introduced as an innovative therapy that addresses modifiable risk factors in patients undergoing surgery for lumbar radiculopathy. PPNE reconceptualizes pain, informs patients about their pain development and is well established for improving maladaptive cognitions in several chronic pain-populations. Hence, we hypothesize that PPNE will be more effective than perioperative biomedical education in improving postsurgical quality of life, pain, analgesic use and return to work in patients at risk for unfavorable outcome following surgery for lumbar radiculopathy. First, a multicentric randomized controlled trial will compare the therapy effects of PPNE to perioperative biomedical education in these at-risk patients. Next, the mediating role of changes in maladaptive cognitions, such as fear of movement and pain catastrophizing, on the therapy effect of PPNE will be investigated.
Study details
- Official title
- The Effectiveness of Pain Neuroscience Education in Patients at Risk for Unfavorable Outcome Following Surgery for Lumbar Radiculopathy: A Multicentric Randomized Controlled Trial
- Conditions
- Interventions
- Behavioral: Perioperative Pain Neuroscience Education
- Behavioral: Perioperative Biomedical Education
- Sponsor
- Vrije Universiteit Brussel
- Collaborators
- Universitair Ziekenhuis Brussel; Research Foundation Flanders
- Start date
- 2021-09-30
- Primary completion
- 2023-10-16
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Belgium
- Total sites listed
- 4
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Scheduled for surgery for lumbar radiculopathy * Aged 18 years or older * Willing to comply with pre-determined follow-up * Speaking and reading Dutch fluently * No new treatments/medication 3 weeks prior to participation and during the trial * Having chronic back and/or leg pain ≥ 6 months * Scoring ≥ 37/68 on the Tampa Scale for Kinesiophobia * Scoring ≥ 30/52 on the Pain Catastrophizing Scale Exclusion Criteria: * Surgery for another condition * Symptoms of cord compression or bilateral leg pain * Other chronic illness characterized by chronic pain * Other chronic rheumatoid, neurological, endocrinological, psychiatric or cognitive disorders * Indicated cognitive impairment (Scoring ≤11/15 on the 5-min Telephone Montreal Cognitive Assessment) * Pregnant or have given birth during the past year * No access to computer, or mobile device at home * Complications during the surgery
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05047679