Analyzing the Brain Alterations of Acupuncture on Patients With CP/CPPS Evaluated by fMRI
Unknown statusNot applicableNCT05075551
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is one of the most common diseases in urology, but its pathogenesis remains unclear and the effective therapy lacks. As a kind of chronic pain which the patients suffered for more than 3 months, CP/CPPS could be alleviated by acupuncture. Functional magnetic resonance imaging (fMRI) and higher magnetic field strengths could enable scientists to investigate the brain accurately and non-invasively during every stage of chronic pain.To avoid placebo effect, sham acupuncture would be also enrolled.Herein, by the utilization of fMRI in resting-state, we investigated the influence on patients' brain alterations after the patients accepted the treatment of acupuncture.
Study details
- Official title
- Analyzing the Brain Alterations of Acupuncture on Patients With Chronic Prostatitis/Chronic Pelvic Pain Syndrome Evaluated by fMRI: Study Protocol for a Randomized Trial
- Interventions
- Device: Acupuncture
- Device: Sham acupuncture
- Other: fMRI scan
- Sponsor
- Shanghai University of Traditional Chinese Medicine
- Collaborators
- Huashan Hospital
- Start date
- 2022-01-05
- Primary completion
- 2023-09-12
- Sex
- Male
- Age range
- from 20 Years to 50 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- China
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: (1)The clinical diagnosis of CP/CPPS is exclusionary diagnosis.The main steps of diagnosing CP/CPPS are follwing: T 1. he chief complaint is long-term recurrent pain or discomfort of lumbosacral and perianal distension in the lower abdomen of the external perineum genital area and the superior pubic area (more than 3 months). 2. Bacterial prostatitis will be eliminated by routine culture of prostatic fluid and urine culture before and after prostatic massage. 3. Urinary tract infection will be ruled out by routine urinalysis and sediment examination. (2)Total score of NIH-CPSI ≥ 15. Exclusion Criteria: The participants would be excluded if they got any acute or chronic infectious disease, other chronic pain diseases, internal organic diseases, history of malignant tumors, and chronic diseases that might contribute to peripheral nerve injury like diabetes mellitus and hypertension. Prostate changes will be observed by prostate ultrasound and other urogenital and pelvic space-occupying lesions will be excluded. Contraindications of fMRI scan like claustrophobia and denture implantation status are also considered.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05075551