Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy
CompletedNCT05083338
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This study learns if depression, anxiety, and catastrophizing (thought patterns that prompt people to expect the worst) are associated with chronic pain after surgery among patients who are scheduled to have cytoreductive surgery with intraoperative hyperthermic chemotherapy. Information from this study may improve the understanding of persistent and chronic postsurgical pain integrating multiple layers of biological and behavioral sciences.
Study details
- Official title
- Prospective Evaluation of Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy in Adult Patients
- Conditions
- Appendix Carcinoma
- Carcinomatosis
- Colorectal Carcinoma
- Gastric Carcinoma
- Malignant Peritoneal Neoplasm
- Malignant Solid Neoplasm
- Interventions
- Procedure: Biospecimen Collection
- Procedure: Pain Assessment
- Other: Questionnaire Administration
- Sponsor
- M.D. Anderson Cancer Center
- Start date
- 2021-08-10
- Primary completion
- 2024-02-09
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * 18 years of age or older; with or without history of preoperative abdominal pain * American Society of Anesthesiologists physical status (ASA) 1-4 * Scheduled surgery: open CRS-HIPEC surgery for primary peritoneal malignancy or secondary carcinomatosis (i.e., appendiceal, colorectal and gastric cancers) * Written informed consent Exclusion Criteria: * ASA \>= 4 or emergency surgeries * Patients with extra-abdominal metastatic disease * Patients cognitive or neurologically unable to complete questionnaires preoperatively * Non-English-speaking patients * Pregnant women
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05083338