Evaluation of Flexofytol® PLUS in Hand Joint Chronic Dyscomfort.

Inclusion Criteria: * Older dan 45 years old, * With hand joint chronic discomfort, * Regularly uses of paracetamol or NSAIDs to manage pain, * Painful symptoms must have been present for more than 6 months, * The patient assesses their pain on a visual pain scale and must be greater than 4 out of 10 over the last 48 hours. Exclusion Criteria: * Related to previous and associated treatments: * Corticosteroids injection in the 3 previous months, whatever the joint concerned, * Use of Slow-acting drugs for OA and/or dietary supplements taken within less than 6 months prior to the study (ex: chondroitin sulfate, diacerein, soy and avocado unsaponifiables, oxaceprol, granions de cuivre, glucosamine, phytotherapy or homeopathy for hand joint discomfort..), * Anticoagulant (coumarinic) treatment and heparin, * General corticotherapy in the 3 previous months, * Contraindication to paracetamol, curcumin, boswellia and NSAID's. * Related to associated pathologies: * Patient suffering from serious associated illness (liver failure, kidney failure, non-controlled cardiovascular diseases...), * The patient has rheumatoid arthritis or gout, * The patient has a bile obstruction. * Related to patient: * Pregnant or breastfeeding women.