EPPIC: Easing Pelvic Pain Interventions Clinical Research Program
RecruitingNot applicableNCT05127616
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The EPPIC (Easing Pelvic Pain Interventions Clinical Research Program) study evaluates an ultra-brief, 4 session cognitive behavioral pain treatment transdiagnostic in design for urologic chronic pain syndrome (UCPPS) with clinical and practical advantages over existing behavioral therapies whose length and focus limits their adoption by clinicians and coverage for mechanistically similar comorbidities. A theoretically informed, practical, empirically grounded approach will systematically unpack CBT's working mechanisms, clarify for whom it works, ease dissemination, appeal to patients, providers, payers, and policy makers in the COVID-19 era favoring low resource intensity treatments, and reduce cost and inefficiencies associated with high intensity therapies whose complexity, length, and scarcity restricts uptake and impact.
Study details
- Official title
- A Brief, Transdiagnostic Cognitive Behavioral Treatment for Urological Chronic Pelvic Pain Syndrome: Processes, Predictions, Outcomes
- Conditions
- Urologic Chronic Pelvic Pain Syndrome (UCPPS)
- Interstitial Cystitis
- Bladder Pain Syndrome
- Chronic Prostatitis
- Chronic Pain
- Chronic Pelvic Pain Syndrome
- Chronic Overlapping Pain Disorders
- Interventions
- Behavioral: Minimal Contact-Cognitive Behavior Therapy
- Behavioral: Patient Education/Support
- Sponsor
- State University of New York at Buffalo
- Collaborators
- University of California, Los Angeles; University of Michigan
- Start date
- 2022-08-10
- Primary completion
- 2028-02
- Sex
- All
- Age range
- from 18 Years to 70 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 3
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Ages 18-70 years (inclusive) * Male or female * All genders, races, ethnic groups * MD-confirmed diagnosis of IC/BPS or CP/CPPS by study urologist or urogynecologist * Pelvic pain including uncomfortable sensations of pressure or discomfort that are not described as outright pain) of at least six months duration * Pelvic pain intensity of at least moderate severity (defined as 3 or greater on a 0-10 Numerical Rating Scale and causes life interference weekly and limit(s) participant's life or work-related activities, general activity level, and/or enjoyment of life) over the past 3 months. * Ability to understand and provide informed consent * Either not taking medications or if taking medications willing to refrain from starting new medications until after the initial 2-week pre-treatment baseline period ends unless medically necessary. * A minimum 6th grade reading level based on the Wide Range Achievement Test (WRAT 4) * Willing to be randomized to either CBT or Support/Education and to follow the protocol to which s/he has been assigned * Willing to be contacted for follow up assessments at week 12 and 3, 6 months after treatment ends * Willing to attend sessions * Able to maintain symptom diaries and complete paper work * Access to telephone and computer or smartphone * Willing and able to provide adequate information for locator purposes Exclusion Criteria: Urologic-Specific * Presence of a neurological condition (e.g., MS, Parkinson's disease, paraplegia) affecting the bladder * The presence of a symptomatic urethral stricture (males only) * History of cystitis caused by tuberculosis or radiation or chemotherapies * Participant has been diagnosed and treated for a pelvic-related malignancy (colon, bladder, prostate, ovarian, endometrial, uterine, testicular, penile, cervical, vaginal, or rectal cancer) Exclusion Criteria: General * Participant has a medical condition(s) whose nature or severity (unstable, life threatening, etc.) would influence adversely the conduct of the clinical trial, confound interpretation of study results, and/or compromise volunteer safety and engagement with study demands. * Gross cognitive impairment, deafness, blindness, vision problems (severe), hearing problems (severe) * Has a major psychiatric disorder which would impede conduct of the clinical study. These clinical disorders would include but are not limited to major depression with a high risk of suicidal behavior (i.e. intent or plan), current …
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05127616