Investigation of Low-intensity Focused Ultrasound for Human Pain Management
CompletedNot applicableNCT05145426
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This project examines the effects of noninvasive brain stimulation on pain. The investigators believe this study will help to better understand possible treatments for chronic pain patients. Participants undergo structural imaging, a functional Magnetic Resonance Image (fMRI) and computed tomography (CT). These images are used to align the low-intensity focused ultrasound (LIFU) device which uses sound waves to temporarily change brain activity. Pain testing is done using a small device that will increase/decrease the temperature of the skin. Brain signals are collected using electroencephalography (EEG). Heart rate, blood pressure, and skin moisture will be monitored as well.
Study details
- Official title
- Investigation of Low-intensity Focused Ultrasound for Human Pain Management
- Conditions
- Interventions
- Device: Low Intensity Focused Ultrasound
- Sponsor
- Virginia Polytechnic Institute and State University
- Start date
- 2022-02-04
- Primary completion
- 2025-07-23
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Understand and speak English Exclusion Criteria: * MRI/CT/EEG contraindications. 1. Claustrophobia 2. Contraindications to MRI: including pacemaker, aneurysm clips, neurostimulators, cochlear implants, metal in eyes, steel worker, or other implants. 3. Contraindications to CT: pregnancy 4. Active medical disorder or treatment with potential CNS effects 5. History of neurologic disorder 6. History of head injury resulting in loss of consciousness for \>10 minutes. 7. History of alcohol or drug dependence 8. Failure to provide Social Security Number or Tax ID number. This is required for tax purposes or payment cannot be processed.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05145426