Mechanisms of Chiropractic Spinal Manipulation for Chronic Low Back Pain
CompletedNot applicableNCT05162924
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This is a mechanistic randomized controlled trial on the effects of chiropractic spinal manipulative therapy on patients with chronic low back pain. It is designed as a mechanistic trial, in which the main objective is to identify which variables related to central sensitization can help predict the response to spinal manipulation, and the evolution of which of these variables can help explain clinical changes in chronic low back pain patients receiving spinal manipulative therapy.
Study details
- Official title
- Efficacy of Chiropractic Spinal Manipulative Therapy in Patients With Primary Chronic Low Back Pain: a Mechanistic Randomized Controlled Trial
- Conditions
- Interventions
- Sponsor
- Real Centro Universitario Maria Cristina
- Collaborators
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz; Université du Québec à Trois-Rivières; University of Alcala
- Start date
- 2021-12-17
- Primary completion
- 2022-12-30
- Sex
- All
- Age range
- from 18 Years to 70 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Spain
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Healthy volunteers will be accepted for that specific comparison group. Those volunteers must demonstrate no evidence of any systemic pathology, inflammatory, psychiatric, neurological or pain condition. Inclusion Criteria: * diagnosis of primary chronic low back pain (performed in the initial evaluation or previously received by a healthcare professional), with or without leg pain * minimum of three months of duration Exclusion Criteria: * diagnosis of neuropathic pain in the lower extremity * evidence of specific pathology affecting the lumbar spine * diagnosis of psychiatric disorder or pain disorder affecting the hand/thumb or in the vicinity of the lumbar area * intake corticosteroids, opioids or anticytokine medications * pregnancy * having been treated with spinal manipulation in the previous 12 months
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05162924