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Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome

CompletedNCT05185180
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

This study seeks to identify defects in immune activation or regulation that may affect a subset of patients with CP/CPPS. This subset appears to have a reduced ability to mount a regulatory immune response, while simultaneously eliciting an exaggerated activated immune response. The defects that we demonstrate appear to be linked to altered methylation of genes involved in both immune regulation and immune activation. The aims of this study will provide definitive evidence of a role for epigenetic changes in immune cells in patients with CP/CPPS.

Study details

Official title
Effects of Epigenetic Regulation in Chronic Pelvic Pain Syndrome
Sponsor
Northwestern University
Start date
2021-10-11
Primary completion
2023-03-07
Sex
Male
Age range
from 21 Years to 80 Years
Results posted
Yes, on ClinicalTrials.gov
Countries
United States
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: Inclusion Criteria for Control Group: • Healthy males ages 21-80 years old Exclusion Criteria: Exclusion Criteria for Control Group: * Females * Males \<21 and \>80 years old * Patients with impaired renal or hepatic function.

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05185180