Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy
RecruitingNCT05197946
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The investigators hope to use MRI biomarkers to identify and characterize sensorimotor network disruption patterns associated with chronic pain and sensory deficits in CP. Investigators will use existing information in the medical record as well as subjective reports from interview, physical exam data, and anatomical and functional MRI data to non-invasively identify brain injury correlates of pain and sensory deficits.
Study details
- Official title
- Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy
- Conditions
- Interventions
- Diagnostic test: MRI
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
- Collaborators
- Johns Hopkins University; Mount Washington Pediatric Hospital; Neurosurgery Pain Research Institute; Cerebral Palsy Alliance
- Start date
- 2018-12-04
- Primary completion
- 2028-12
- Sex
- All
- Age range
- from 8 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 4
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Participants with CP (Survey-only): Inclusion Criteria: * Individual 8+ years of age * Diagnosis of cerebral palsy Exclusion Criteria: -None Neurotypical participants: (Survey-only): Inclusion Criteria: * Individual 8+ years of age * Adult subject able to indicate understanding and affirmative consent OR Adult/child subject unable to indicate understanding and affirmative consent AND subject assents AND LAR consents Exclusion Criteria: -Clinically-significant neurologic or developmental diagnosis Participants with CP (Survey and MRI): Inclusion Criteria: * Individual 8+ years of age * Adult subject able to indicate understanding and affirmative consent OR Adult subject unable to indicate understanding and affirmative consent AND subject assents AND LAR consents * Diagnosis of cerebral palsy * Clinical imaging demonstrating isolated periventricular white matter injury * Clinical judgment that all neurologic symptoms are attributable to non-progressive periventricular white matter injury * Able to lie still in scanner for 1.5 hours in at most 2 sessions and be able to have MRI Exclusion Criteria: -None Neurotypical participants (Survey and MRI): Inclusion Criteria: * Individual 8+ years of age * Adult subject able to indicate understanding and affirmative consent * Able to lie still in scanner for 1.5 hours and be able to have MRI Exclusion Criteria: -Clinically-significant neurologic or developmental diagnosis
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05197946