Chronic Pain and Hemophilia
Active, not recruitingNCT05202951
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Hemophilia (A and B) are X-linked hereditary bleeding disorders whose severity depends on the level of coagulation factor (FVIII or FIX respectively). Bleeding is mainly from joints (hemarthrosis) and muscles (hematoma). Nowadays, treatment is based on preventive or curative intravenous infusion of coagulation factor concentrates. Despite these treatments, there is joint deterioration that can be responsible for hemophilic arthropathy and chronic pain. This pain may be related to excess nociception during acute bleeding, but it may also be neuropathic. There are only a few studies that have looked at pain in hemophilia, but it is accepted that the vast majority of patients (especially those with severe forms) suffer from chronic pain. Because patients have become accustomed to this pain and physicians are still not very aware of how to assess it, this pain is not treated effectively. In order to better manage pain in hemophilia, it is therefore necessary to characterize their pain and to know the nociceptive or neuropathic component. The aim of our study is therefore to study the prevalence, the nociceptive or neuropathic profile, the chronic aspect of pain and the main locations of pain in hemophilia. In addition to raising the awareness of physicians in the centers about pain management using specific questionnaires, this survey will help to better define chronic pain in hemophilia of all severities.
Study details
- Official title
- Status of Chronic Pain in Patients With Hemophilia.
- Conditions
- Chronic Pain
- Hemophilia
- Interventions
- Sponsor
- University Hospital, Clermont-Ferrand
- Start date
- 2022-02-28
- Primary completion
- 2025-12-18
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- France
- Total sites listed
- 10
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Patient with haemophilia of any severity, * Carrier female with low levels haemophilia (\< 40%), * ≥ 18 years of age and capable of giving informed consent to participate in research. Exclusion Criteria: * Patient's refusal to participate in the survey, * Patient does not understand enough French (written and spoken) to complete the survey, * Patient unable to complete the survey for logistical reasons (lack of internet access), * Patient under protective measures (guardianship), * Patients with known addictive comorbidities and/or cognitive disorders.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05202951