Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
RecruitingNCT05277025
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
Study details
- Official title
- Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
- Conditions
- Sponsor
- University of Florida
- Start date
- 2022-03-22
- Primary completion
- 2027-07-28
- Sex
- All
- Age range
- from 18 Years to 70 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Ages 18-70 * Fulfills the 1990 and 2011 American College of Rheumatology Criteria for FM * Fulfills the 2010 ACR-EULAR classification criteria for RA * Healthy volunteers: No significant pain/fatigue/depression/anxiety. Exclusion Criteria: * Diabetes * Cancer * Advanced liver, kidney or cardiovascular disease * Neuropathic pain
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05277025