Topical Sevoflurane for Treatment of Chronic Leg Ulcers
RecruitingPhase 4NCT05303805
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Patients with painful non-healing leg ulcer will be enrolled in the clinical single-blinded randomized study. The active treatment group will have sevoflurane applied at approximately 1 ml/cm2 at the start of wound treatment, the control group will only have a standard rinse solution with Cyteal TM (Pierre Fabre Medicament, France). Further treatment will then be carried out in the standard manner. The duration of the study will be 5 days; if the defect heals earlier, it will be terminated early. Exclusion criteria: allergy to sevoflurane, inability to understand the questionnaire Parameters to be monitored will be pain intensity, microbial colonization, appearance and size of the defect
Study details
- Official title
- Analgesic and Healing Effect of Topical Sevoflurane for Chronic Venous Ulcers
- Conditions
- Leg Ulcer
- Interventions
- Drug: Sevoflurane
- Combination product: Cyteal
- Sponsor
- Charles University, Czech Republic
- Collaborators
- Faculty Hospital Kralovske Vinohrady
- Start date
- 2022-05-02
- Primary completion
- 2026-04-30
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Czechia
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Patients with painful (pain intensity on the numerical scale NRS 0-10 is NRS\>4) non- healing tibial venous ulcers Exclusion Criteria: * Allergy to sevoflurane * Inability to understand the pain-intensity questionnaire
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05303805