High Intensity Training to Improve Diaphragm Functioning in Persons With Chronic Nonspecific Low Back Pain
Unknown statusNot applicableNCT05384457
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This randomized controlled trial aims to investigate 1) the effects of high intensity training (HIT) compared to moderate intensity training (MIT) on diaphragm muscle strength, -endurance, -fatigue and -activation, 2) to which extent these changes in diaphragm functioning are related to changes in cardiorespiratory fitness, postural control, pain and disability after HIT versus MIT, 3) to which extent depressive mood and anxiety moderate the effects of HIT on diaphragm functioning in persons with chronic nonspecific low back pain (CNSLBP). The investigators hypothize that HIT improves diaphragm functioning more compared to MIT in persons with CNSLBP.
Study details
- Official title
- The Breathe-(H)IT Trial: Multimodal High Intensity Training to Improve Diaphragm Functioning in Persons With Chronic Nonspecific Low Back Pain
- Interventions
- Other: High intensity training
- Other: Moderate intensity training
- Sponsor
- Hasselt University
- Collaborators
- KU Leuven; Maastricht University
- Start date
- 2022-08-22
- Primary completion
- 2025-06-01
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Belgium
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criterian (CNSLBP patients): * Dutch-speaking * Adults (age 18-65 years) * Chronic low back pain (i.e. pain localized below the costal margin and above the inferior gluteal folds, with or without referred leg pain for a period of at least twelve weeks), with a non-specific origin (i.e. pain of a nociceptive mechanical nature, not attributable to a recognizable, known, specific pathology, e.g. infection, tumour, osteoporosis, fracture, structural deformity, inflammatory disorder, radicular syndrome, or cauda equina syndrome) Exclusion Criteria (CNSLBP patients): * History of spinal fusion * A musculoskeletal disorder aside from chronic nonspecific low back pain that could affect the correct execution of the therapy program * Baseline characteristics that could affect the evaluation of the outcomes (a pacemaker, a chronic obstructive respiratory disorder, or known balance/vestibular problems) * Severe comorbidities (e.g., paresis or sensory disturbances of neurological origin, diabetes mellitus, rheumatoid arthritis) * Ongoing compensation claims * Negative advice from the general practitioner regarding sports medical screening * Pregnancy * Persons that are not able to attend regular appointments Inclusion Criteria (healthy volunteers): * Dutch-speaking * Adults (age 18-65 years) * No acute or chronic complaints Exclusion Criteria (healthy volunteers): * History of spinal fusion * Baseline characteristics that could affect the evaluation of the outcomes (a pacemaker, a chronic obstructive respiratory disorder, or known balance/vestibular problems) * Severe comorbidities (e.g., paresis or sensory disturbances of neurological origin, diabetes mellitus, rheumatoid arthritis) * Ongoing compensation claims * Negative advice from the general practitioner regarding sports medical screening * Pregnancy
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05384457