Home-based EEG Neurofeedback for Chronic Neuropathic Pain
CompletedPhase 1NCT05464199
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
In order to address the growing problem of chronic pain management in the UK, a proof of concept/feasibility open label cohort study has been devised to explore the effectiveness of a home-based self-administered non-pharmacological treatment utilising neurofeedback (NFB) training with a headset and tablet-based software application. This study will replicate the intervention from a previous clinical trial conducted in the UK during the Covid-19 lockdown in 2020/21 (NCT04418362) and extend it by examining EEG activity before, during, and after the intervention, alongside outcome measures, including changes in pain intensity and severity, sleep, mood and quality of life. Ten participants will take part in pre-intervention assessments followed by four weeks of EEG baseline readings (5 times per week for 5 minutes), eight weeks of NFB treatment (5 times per week for 40 mins), and 12 weeks of post treatment EEG baselines readings (5 times per week for 5 minutes). Participants will be provided with training and detailed instructions on how to self-administer the NFB treatment using a bespoke headset and tablet-based software application in the comfort of their own homes. Assessments will be conducted at Week 0 (pre-intervention), Week 4 (pre-NFB treatment), Week 12 (post NFB treatment) and at follow up points (Week 16, 20, and 24). It is anticipated this study will provide evidence of the safety, efficacy, reliability and validity of a low-cost non-pharmacological solution to the physical, psychological and social difficulties experienced by individuals with chronic neuropathic pain conducted within the NHS health system.
Study details
- Official title
- Home-based EEG Neurofeedback to Reduce Chronic Neuropathic Pain, a Cohort Clinical Trial.
- Conditions
- Interventions
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
- Collaborators
- Exsurgo Ltd
- Start date
- 2022-10-06
- Primary completion
- 2023-07-01
- Sex
- All
- Age range
- from 18 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United Kingdom
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Males and females over 18 years of age with ongoing chronic neuropathic pain for 3 months or more * must have had an average pain rating in the last week of equal to or greater than 4/10 on Visual Analogue Scale for Pain * must have a head circumference between 520-620 mm to ensure correct fitment of headset * must have access to a reliable internet connection and Wi-Fi at home * must have and display competence with equipment and headset usage after training Exclusion Criteria: * Previous neurofeedback training * serious recent (within 12 months) head injury and/or traumatic brain injury and/or concussion * diagnosed with a major neurological disorder (e.g. trigeminal neuralgia) * a history of seizures * diagnosed with a major psychiatric disorder * has an implanted electronic neuromodulation device for example - a heart pacemaker, or loop recorder * is unable to provide informed consent * must not have any change in medication or treatment planned in the 1 week prior to and during the trial intervention period, or in the 12 weeks post trial intervention, while EEG baselines are being recorded.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05464199