Identifying Biomarkers for Chronic Pain After Breast Cancer Treatment.
Unknown statusNCT05507034
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Up to 40% of women experience chronic pain after treatment for breast cancer, and this pain is often very disabling. However, chronic pain after breast cancer remains under-recognised and undertreated. An effective and patient-tailored approach of (chronic) pain after breast cancer indeed requires a thorough knowledge and evaluation of the pain. In daily clinical practice, however, guidelines for a comprehensive diagnosis of pain in cancer patients and survivors are lacking. Further research in this topic is crucial for an efficient, preventive as well as curative, approach of pain after breast cancer. Besides the high prevalence and the important impact of pain in this population, the breast cancer population is also an ideal population to study chronic pain and its natural time course in different stages, since most patients start pain-free, but almost half of them end up with chronic pain. Therefore, this study aims to map biomarkers (both predictive, prognostic and diagnostic) for chronic pain after breast cancer treatment. We will study possible biopsychosocial biomarkers in relation to (chronic) pain and monitor their temporal changes from the moment of diagnosis until 1 year after surgery. The potential biomarkers are situated within the medical imaging of the brain, measurements of pain sensitivity and psychological variables.
Study details
- Official title
- sCANsens: Identifying Biomarkers for Chronic Pain After Breast Cancer Treatment
- Conditions
- Neoplasm, Breast
- Carcinoma Breast
- Chronic Pain
- Interventions
- Diagnostic test: Biomarkers
- Sponsor
- Universiteit Antwerpen
- Collaborators
- University Hospital, Antwerp; Fund for Scientific Research, Flanders, Belgium
- Start date
- 2022-10-04
- Primary completion
- 2025-06
- Sex
- Female
- Age range
- from 25 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- Belgium
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Unilateral breast cancer * Pain at enrollment \<3/10 on average during the past week * First cancer diagnosis Exclusion Criteria: * Pre-existing pain conditions * major pre-existing neurological disorders * No recurrent cancer or metastasis * No previous surgery in area
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05507034