Exploring Central Sensitization in Pregnant Women
RecruitingNCT05507853
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Pelvic Girdle Pain (PGP) is reported by 50% of pregnant women and up to 11 years after pregnancy, 10% of women have persistent and per definition chronic PGP. Central (nervous system) sensitization that elicits pain hypersensitivity, may be one explanation. The overall aim of this study is to explore features of central sensitization in pregnant women and its predictive ability on physical activity, functioning and health in women with PGP. Measurements of central sensitization will be done on two study groups, pregnant women with PGP and healthy controls. To identify women at risk to develop chronic pain in relation to a common pain experience ie PGP in pregnancy, may help us understand if central sensitization early in life explains why women develop chronic pain.
Study details
- Official title
- In the Joints or in the Brain? Exploring Central Sensitization in Pregnant Women and Its Role in Pain, Physical Activity, Functioning and Health Following Pregnancy
- Conditions
- Pelvic Girdle Pain
- Chronic Pain
- Sponsor
- Göteborg University
- Collaborators
- Vastra Gotaland Region
- Start date
- 2023-08-15
- Primary completion
- 2025-07-01
- Sex
- Female
- Age range
- from 18 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Sweden
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * pregnant (first time pregnant or previous experience of pregnancy) * 18 years of age or older * have a single foetus pregnancy * be in gestational weeks 20-30 * able to read and understand Swedish or English Exclusion Criteria: * no history of a fracture or malignant disease in the back, pelvis, pelvic floor or hips * no systemic disease of the musculoskeletal or the nervous system * no diseases such as gestational diabetes or diabetes type 1 and 2, hypertension * no obstetric complications * no contradiction for tests.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05507853