Caudal Epidural Prolotherapy Versus Steroids in Failed Back Surgery Syndrome
CompletedPhase 2, Phase 3NCT05548738
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This study will be held on patients with failed back surgery syndrome, the investigators are comparing prolotherapy and steroids injections in caudal epidural space to relieve the pain
Study details
- Official title
- The Efficacy of Ultrasound and Fluoroscopy Guided Caudal Epidural Prolotherapy Versus Steroids for Chronic Pain Management in Failed Back Surgery Syndrome
- Conditions
- Interventions
- Drug: medthylprednisolone
- Drug: prolotherapy
- Sponsor
- Alexandria University
- Start date
- 2022-04-20
- Primary completion
- 2023-11-30
- Sex
- All
- Age range
- from 20 Years to 70 Years
- Results posted
- No results posted in this snapshot
- Countries
- Egypt
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. patients diagnosed with failed back surgery syndrome, having chronic pain for more than 3 months by a detailed assessment including medical history and examination 2. patients having positive radiological (MRI) findings of spinal nerve roots being irritated or compressed after having surgery for one of many conditions including: lumbar disc herniation, spinal canal stenosis, osteophytes, spodylolithesis or foramen stenosis 3. patients whom another surgery is not indicated Exclusion Criteria: 1. patient refusal 2. pregnancy 3. systemic infection or infection at the site of injection 4. patients on anticoagulation 5. immunocompromised patients as uncontrolled diabetes, osteoporosis as a contraindication for steroid injection 6. patients with renal impairment or on dialysis 7. acute disc prolapse as it requires immediate surgery 8. opioid use 9. concurrent significant depressive illness, inflammatory of joint disease.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05548738