Exercise and Pain in CCS
CompletedNot applicableNCT05562193
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to demonstrate that integration of exercise intervention into standard post-cancer directed treatment care will improve patient reported pain, decrease the need for medications to manage chronic pain and improve functional and psychosocial outcomes in survivors of cancers in children and adolescents. Our central hypothesis is that integration of exercise interventions into standard post-cancer directed treatment care will be acceptable and feasible while improving patients' pain, decreasing the cumulative dose of pain medication and improving patients' functional and psychosocial outcomes as compared to patients who only receive standard post-cancer directed treatment care.
Study details
- Official title
- Exercise Intervention Coupled With Standard Post-cancer Directed Treatment Care to Reduce Chronic Pain in Childhood Cancer Survivors Who Have Completed Cancer-directed Therapy Less Than One Year
- Conditions
- Childhood Cancer Survivors
- Interventions
- Behavioral: Physical activity intervention coupled with standard post-cancer directed treatment care
- Other: Standard post-cancer directed treatment care control
- Sponsor
- Milton S. Hershey Medical Center
- Collaborators
- Four Diamonds Research Fund at Penn State Health Childrens Hospital
- Start date
- 2022-09-30
- Primary completion
- 2025-03-11
- Sex
- All
- Age range
- from 10 Years to 17 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Male and female CCS diagnosed with any type of cancer 2. CCS who have completed all standard/planned cancer treatment and are stable at the time of recruitment 3. CCS are \< 1-year post cancer therapy 4. CCS who have chronic pain (pain will be self-reported by the participant, will have to be ≥1 on a scale of 10 and lasting for 3 months or longer) 5. CCS who are age between 10 and 17 years old at the time of enrollment 6. CCS who are and who are not non-ambulatory/wheelchair bound. 7. CCS and parent/legal guardian must be able to speak, read and understand the English language 8. CCS's parent or legal guardian must be able to provide and understand informed consent 9. CCS must be able to provide and understand assent 10. CCS must be able to attend three visits (baseline, 8 and 16-week follow-up) at the Penn State Health Children's Hospital 11. CCS and parent/legal guardian must have access to a computer, smartphone or tablet Note: The agreement of the attending oncologist will be required for the participation of CCS eligible for this study. Exclusion Criteria: 1. CCS who have not completed all standard/planned cancer treatment and/or not in complete remission at the time of recruitment 2. CCS who are \> 1-year post cancer therapy 3. CCS who are \< 10 years old and \> 17 years old at the time of enrollment 4. CCS who have evidence in their medical record of an absolute contraindication to complete any of the physical assessments in their medical record. This exclusion criterion is at the oncologist's discretion when research staff will contact the medical oncologist via secure email or secure message through the electronic medical record for approval to approach their patients for the study and for medical clearance. The oncologists can update this information at any time during the study if there is evidence of an absolute contraindication to complete any of the physical assessments. 5. CCS who have history of refractory or recurrent cancer 6. CCS or their parent/legal guardian who are unable to speak, read, and understand the English language 7. CCS who are unable to access and complete online questionnaires
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05562193