Phrenic Nerve Infiltration in Neck Pain
RecruitingPhase 4NCT05605639
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Neck pain frequently present comorbidities in peridiaphragmatic organs. The innervation of these organs include the phrenic nerve. It is known that peridiaphragmatic organs trigger referred pain in the neck area. As well, previous studies have shown that visceral disorders increase sensitization in somatic tissues. This study aims to analyze the ability of phrenic nerve infiltration to diminish sensitization and improve neck symptoms in the absence of neurological, traumatic or infectious pathology that justifies the pain, by means of a randomized controlled trial.
Study details
- Official title
- Phrenic Afferences In Organic and Metabolic Illness: Central Sensitization
- Conditions
- Interventions
- Drug: Bupivacaine
- Other: Placebo (physiological saline serum infiltration)
- Sponsor
- University of Seville
- Start date
- 2022-11-17
- Primary completion
- 2025-07
- Sex
- All
- Age range
- from 18 Years to 64 Years
- Results posted
- No results posted in this snapshot
- Countries
- Spain
- Total sites listed
- 2
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Over 18 and under 64 years old * Patients attending to the physician or physical therapist with a main complaint of neck pain * Presentation of any peridiaphragmatic visceral disorder. * That the subject agrees to participate in the project by signing the informed consent. Exclusion Criteria: * Illness of neurological, traumatic, oncological, infectious or rheumatic (fibromyalgia, ankylosing spondylitis...) origin. * Uncooperative subject. * Severe psychiatric illness. * Loss of Cognitive Ability. * Contraindication to infiltration of the phrenic nerve. * History of head, spinal or upper limb surgery * History of infiltration for the neck pain in the previous 3 months * History of physical therapy for the neck pain in the previous 30 days
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05605639