Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized Clinical Trial
CompletedNot applicableNCT05627830
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate location of glenoid fossa and the disc space while prolotherapy procedure, and to adjust the needle insertion to according to articular eminence, mandibular condyle, and intra-articular space as anatomical variations. The vibration of ultrasound waves generates a heat so there is a thermal effective for prolotherapy effusion in the TMJ space.
Study details
- Official title
- Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized Clinical Trial
- Conditions
- TMJ Disc Disorder
- Ultrasound Therapy
- Complications
- TMJ
- Prolotherapy
- Internal Derangement
- Clicking Tinnitus
- Injection Site
- Pain, Chronic
- Anterior Disc Displacement
- Myofascial Pain Syndrome
- Masticatory Muscle
- Interventions
- Procedure: Prolotherapy
- Sponsor
- Cairo University
- Start date
- 2022-11-10
- Primary completion
- 2023-05-01
- Sex
- All
- Age range
- from 20 Years to 60 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Egypt
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Patients with TMD - internal derangement with symptomatic clicking pain, according to RDC (Research diagnostic criteria for TMJD) sheet . 2. Muscles spasm causing TMDs. 3. Patients who failed to improve on conservative measures or highly hyperactivity patients. 4. Female and male patients age range from 20 to 60 years old. Exclusion Criteria: 1. Patients who refused to be included in the research. 2. Patients with a systemically diseases or inflammation whether local or generalized. 3. Patients with bleeding disorders. 4. Patients with unknown dextrose allergy.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05627830