Sodium Channel Mutations in Patient With the Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)
Unknown statusNCT05877274
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The goal of this observational study is to learn about sodium channel (Nav) mutations in patients with the Anterior Cutaneous Nerve Entrapment Syndrome (ACNES). This study will give more insight into the pathophysiology of ACNES, which is still largely unknown. The primary objective is to determine if there are mutations of Nav1.7 and Nav1.8 in patients with ACNES. Therefore, one blood sample will be drawn, in which the mutations will be analyzed.
Study details
- Official title
- Sodium Channel Mutations (SCN9A, SCN10A) in the Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)
- Conditions
- Anterior Cutaneous Nerve Entrapment Syndrome
- Nerve Entrapment Syndrome
- Chronic Pain Syndrome
- Interventions
- Other: Sodium channel mutation
- Sponsor
- Maxima Medical Center
- Start date
- 2023-10-03
- Primary completion
- 2024-06
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Netherlands
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: In order to be eligible to participate in this study, a subject must be diagnosed with ACNES and receive treatment at our outpatient clinic. Additionally, subject has to meet one of the following criteria: * Known to have a first- or second-degree relative with ACNES; * Have more than one recurrence of ACNES after a pain free period or ACNES at multiple locations in the abdominal wall; * Persistent pain after posterior neurectomy. Exclusion Criteria: * Inability to understand Dutch language. * Known neuromuscular or neurodegenerative disease.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05877274