Intercostal Cryoanalgesia for Chronic Pain After VATS Lung Resection
CompletedNot applicableNCT05884099
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Brief summary (from the registry)
Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection paravertebral block for the prevention of chronic thoracic pain after VATS lung resection surgery.
Study details
- Official title
- Intercostal Cryoanalgesia for Prevention of Chronic Postoperative Pain Following Video-assisted Thoracoscopic Lung Cancer Resection
- Conditions
- Cryotherapy Effect
- Chronic Pain
- Lung Cancer
- Surgery
- Interventions
- Procedure: Cryoanalgesia AND single-injection paravertebral block
- Procedure: Single-injection paravertebral block
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
- Start date
- 2023-11-09
- Primary completion
- 2025-01-21
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Canada
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Patients scheduled for elective anatomical pulmonary resection (anatomical segmentectomy, lobectomy or bilobectomy) by VATS for lung cancer * American Society of Anesthesiologists (ASA) score 1-3 Exclusion Criteria: * Contraindication to the paravertebral block (coagulopathy, discontinuous paravertebral space, impossible thoracoscopic visualization of the paravertebral space) * Contraindication to intercostal cryoanalgesia (cold urticaria, cryoglobulinemia) * Epidural analgesia preferred (high risk of thoracotomy, marginal lung function) * Surgical criteria (conversion to thoracotomy, non anatomical wedge resection) * Preoperative thoracic or shoulder pain on the operated side * Known allergy to acetaminophen, celecoxib, sulfa, or both hydromorphone and morphine * History of thoracic surgery on the operated site * Regular use of opioids or medication with effects against neuropathic pain (tricyclics, gabapentinoids, duloxetine, venlafaxine) * Inability to understand pain scales or to communicate clearly despite adequate teaching * Contraindication to non-steroidal anti-inflammatory drugs (renal filtration rate \< 60 mL/min, active gastric ulcer) * Pregnancy * Patient refusal to participate
Canadian sites (1)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05884099