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Topical Cannabis for Chronic Musculoskeletal Pain

Unknown statusNCT05908552
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

Our proposal objective is to evaluate if state-regulated topical CBD-based products relieve chronic musculoskeletal pain and/or absorb into the bloodstream.

Study details

Official title
A Novel Non-Opioid Topical Therapy for Chronic Musculoskeletal Pain
Sponsor
University of Colorado, Denver
Start date
2023-07-01
Primary completion
2024-04-30
Sex
All
Age range
from 21 Years to 85 Years
Results posted
No results posted in this snapshot
Total sites listed
0

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Some inclusion/exclusion criteria are purposely omitted at this time to preserve scientific integrity. They will be included after the trial is complete. Inclusion Criteria: * Chronic peripheral joint pain * Desire and intent to use a topical cannabinoid product containing cannabidiol (CBD) or a combination of CBD and tetrahydrocannabinol (THC) to alleviate this pain Exclusion Criteria: * Current or prior use of topical cannabis * Unwilling or unable to discontinue other (non-topical) cannabis use for four weeks prior to and during study participation through week two * Intent to use a THC-predominant topical product (ratio greater than 1:1 of THC to CBD) * Current or history of substance use disorder * History or diagnosis of schizophrenia, bipolar or a psychotic disorder * Surgery on the affected musculoskeletal location within the 3 months prior to enrollment * Planned surgery or procedure on the affected musculoskeletal location during participation in the study * Allergy or prior severe adverse reaction to cannabis (cardiovascular event, psychosis, etc) * Current or prior cannabis abuse/dependence * Cognitive disability that interferes with ability to provide consent or understand study procedures * History of seizure disorder * Pending legal action or workers compensation * Pregnant females or females intending to become pregnant during the study period * Lactating females * Chronic/severe medical illness (renal disease, liver disease, cancer, significant cardiovascular disease, or history of myocardial infarction) * Active component military

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05908552