Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain
RecruitingNCT05963451
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Brief summary (from the registry)
The goal of this observational study is to better understand the role of the brain in chronic low back pain patients.
Study details
- Official title
- Assessing the Predictability of Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain
- Conditions
- Interventions
- Sponsor
- Université de Sherbrooke
- Start date
- 2023-09-07
- Primary completion
- 2027-07-16
- Sex
- All
- Age range
- from 18 Years to 75 Years
- Results posted
- No results posted in this snapshot
- Countries
- Canada
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Low back pain (≥ 6 months) with or without pain radiating to the legs or radiating to the neck * Positive medial branch blocks, suggesting that the pain originates from the lumbar facet joints * Average pain intensity of ≥ 3/10 in the 24-hour period before the initial visit * Pain primarily localized in the lower back Exclusion Criteria: * Inadequate pain relief or relief of less than three months following selective thermoablation of medial lumbar branches by radiofrequency * Neurological, cardiovascular, or pulmonary disorders * Comorbid pain syndrome * History of surgical intervention in the back * A corticosteroid infiltration within the past year * Pregnancy (current or planned during the course of the study) * Contra-indication to Magnetic Resonance Imaging (MRI)
Canadian sites (1)
| Facility | City | Province |
|---|---|---|
| Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS) | Sherbrooke | Quebec |
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05963451