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Conditioned Pain Modulation in Localized vs Widespread Chronic Low Back Pain

Unknown statusNCT05972395
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

This study aims to compare function of the body's endogenous pain modulation system between people with localized low back pain versus widespread body pain. Endogenous pain modulation refers to the body's natural ability to inhibit one pain stimulus by applying a second pain stimulus. This study will assess pain inhibition by measuring pressure pain thresholds at the low back before and during cold water hand immersion. The researchers hypothesize that those with widespread body pain will have worse functioning of pain inhibition compared to those with localized low back pain only. The results may provide insights into personalized chronic pain management approaches.

Study details

Official title
Determining if Conditioned Pain Modulation Differs Between Individuals With Localized Versus Widespread Mechanical Pain Hypersensitivity in Chronic Low Back Pain
Interventions
  • Other: Localized vs Widespread Mechanical Pain Hypersensitivity
Sponsor
Ahram Canadian University
Start date
2023-07-28
Primary completion
2024-02-25
Sex
All
Age range
from 18 Years to 60 Years
Results posted
No results posted in this snapshot
Countries
Egypt
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Ages 18-60 years * Chronic LBP \>3 months * Average LBP intensity ≥4/10 Exclusion Criteria: * Known LBP pathologies * Previous lumbar surgery * Neuropathic LBP * Comorbid generalized pain conditions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT05972395