Traumatic Events in Childhood, Attachment, Pain Perception, Epigenetic Marks, Quality of Life and Resilience.
CompletedNCT06077097
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
In the present research study, aiming to explore the links between several psychological factors and chronic pain, the research seeks to develop an inclusive framework to investigate the role of adverse childhood experiences (ACEs) in patients' pain perception and overall quality of life throughout their pain management programs. Specifically, attachment styles (AS) and pain-related resilience processes are considered as potential mediators of the effectiveness of chronic pain management programs. Additionally, biological measures are proposed to investigate physiological parameters of pain and to further explore the degree of consistency between self-reported measures, ACEs, ASs, chronic stress, and several epigenetic biomarkers.
Study details
- Official title
- Traumatic Events in Childhood, Attachment, Pain Perception, Epigenetic Marks, Quality of Life and Resilience: When Psychological Dimensions Interfere With the Hospital Management of Pain
- Conditions
- Chronic Pain
- Adverse Childhood Experiences
- Attachment Styles
- Chronic Stress
- Resilience, Psychological
- Quality of Life
- Epigenesis, Genetic
- Interventions
- Genetic: Biological samples
- Sponsor
- University of Lorraine
- Start date
- 2023-04-12
- Primary completion
- 2024-12-18
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- France
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Have a chronic pain syndrome persisting for at least six months * Have been referred to a chronic pain management programme at the Centre of evaluation and treatment of chronic pain at the "Belle- Isle" hospital (private hospital in Metz, France) or at the Pain Consultation of the Regional University Hospital of Nancy, France * Be between 18 and 65 years old * Be able to read and write in French (be able to understand the information and fill in the questionnaires independently) * Agree to participate in the project and sign the consent form Exclusion Criteria: * Have received pain management in a specialised chronic pain facility (of any kind) during their lifetime * Have physical, cognitive and/or linguistic deficiencies that make it impossible to fill in the questionnaires * Have a psychiatric history (psychosis type) * Have a drug or alcohol dependency * Be a protected adult, under guardianship or curatorship * Being pregnant or breastfeeding
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06077097