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CSF Single-cell Sequencing and Proteomics of Chronic Postsurgical Pain in Patients With Lower Limb Fractures

Unknown statusNCT06126289
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

The purpose of this study is to assess the proteomics and transcriptomic differences between pain-free control subjects and patients with chronic postoperative pain through single-cell sequencing technology.

Study details

Official title
Cerebrospinal Fluid Single-cell Sequencing and Proteomics Analysis of the Chronic Postsurgical Pain in Patients Following Open Reduction Internal Fixation of Lower Limb Fractures
Sponsor
Xuzhou Central Hospital
Start date
2023-12-25
Primary completion
2025-07-30
Sex
All
Results posted
No results posted in this snapshot
Total sites listed
0

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. ASA physical status 1 to 3 (males and females) 2. Undergone open reduction and internal fixation of the lower limbs and plan to take out the internal fixation under spinal anesthesia Exclusion Criteria: 1. Absence of written consent 2. Contraindication to regional anaesthesia 3. Known dementia at time of operation 4. History or opioid abuse 5. Unexpected conversion of general anesthesia or surgery is not carried out

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06126289