Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
RecruitingNot applicableNCT06214923
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Study details
- Official title
- Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
- Conditions
- Interventions
- Device: RelieVRx
- Device: Sham-VR
- Other: No-VR (natural history control)
- Sponsor
- University of Maryland, Baltimore
- Start date
- 2024-04-09
- Primary completion
- 2026-05-30
- Sex
- All
- Age range
- from 18 Years to 88 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 2
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Age (18-88 years) * English speaker (written and spoken) * Temporal Mandibular Disorder (TMD) for at least 3 months * TMD Grade Chronic Pain Scale (GCPS) ≥ 0 Exclusion Criteria: * Present or past degenerative neuromuscular disease * Cardiovascular, neurological diseases, pulmonary abnormalities, kidney disease, liver disease, history of cancer within past 3 years * Cervical pain (e.g. stenosis, radiculopathy) * Any personal (or family first degree) history of mania, schizophrenia, or other psychoses * Severe psychiatric condition (e.g. schizophrenia, bipolar disorders, autism) leading to hospitalization within the last 3 years. * Use of Antipsychotics (e.g., Risperdal, Ability and clozaril)Lifetime alcohol/drug dependence or alcohol/drug abuse in past 3 months * Pregnancy or breast feeding * Color-blindness * Impaired or uncorrected hearing * Non-dominant hand * Any facial trauma that has occurred in the last 6 weeks * History of a severe facial trauma in the last 2-3 months * Conditions that would interfere with the VR mask placement (e.g. trauma, burn, infection) * Known history of severe motion sickness * Non-removable head cover, artificial hair, certain types of braids or dreadlocks * History of fainting * History of angioedema * Failed drug test (testing for opiates, cocaine, methamphetamines, and amphetamines)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06214923