Comparison of Unilateral and Bilateral Transforaminal Epidural Steroid Injection
CompletedNot applicableNCT06240793
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Lumbar radicular pain affects the person's quality of life. The most common cause of lumbar radicular pain is disc herniation. In radicular pain due to lumbar disc herniation, epidural steroid injections are frequently applied to patients who do not benefit from medical treatment and physical medicine modalities. Epidural steroid injection inhibits the synthesis and release of pro-inflammatory substances that develop as a result of mechanical compression.In the transforaminal epidural technique, the solution is administered to the anterior epidural space and spreads to the ipsilateral periradicular area. The applied solution does not cross the midline and there is no contralateral drug spread. Although bilateral transforaminal epidural steroid injection is recommended in unilateral lumbosacral disc herniation because the inflammation is bilateral, unilateral transforaminal steroid injection has been applied in most studies. We aimed to to evaluate the effects of unilateral and bilateral transforaminal epidural steroid injection on pain intensity, functionality and medication use in unilateral lumbosacral disc herniation
Study details
- Official title
- Comparison of Unilateral and Bilateral Transforaminal Epidural Steroid Injection in Unilateral Lumbosacral Disc Herniation: a Randomized Controlled Trial
- Conditions
- Interventions
- Procedure: unilateral transforaminal epidural steroid block
- Procedure: bilateral transforaminal epidural steroid block
- Sponsor
- Ankara University
- Start date
- 2023-06-15
- Primary completion
- 2023-10-15
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- Turkey (Türkiye)
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Patients aged 18-65 * Patients with unilateral lumbosacral radicular pain for at least 3 months * Lumbosacral radicular pain is confirmed by Magnetic Resonance Imaging (MRI) and physical examination and the pain is secondary to unilateral lumbosacral disc herniation. * Patients who did not respond to conservative treatment (medical and physical medicine modalities) * Pain intensity measured using Numeric Rating Scala (NRS) is 4 or more Exclusion Criteria: * Patients with previous lumbar surgery * Presence of psychiatric disease that is unstable/not controlled by medical treatment * Pregnant patients * Those with bleeding diathesis * Patients who received epidural steroid injection within the last year * Patients with known allergies to the substances administered during the procedure (local anesthetic, steroid, contrast material) * Patients with scoliosis, spondylolisthesis, central canal stenosis, compression fracture, previous discitis, sequestered disc, bilateral disc herniation
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06240793