Pharmacokinetics of AUX-001 40mg Once-daily in Healthy Subjects Under Fasting and Fed Conditions

Inclusion Criteria: 1. Free written informed consent signed and dated prior to any procedure required by the study. 2. Male or female subject between 18 and 55years, inclusive, at the time of signing the informed consent. 3. Body mass index (BMI) of 18.0 to 31.0 kg/m2, inclusive. 4. No clinically relevant diseases captured in medical history. 5. No clinically relevant abnormalities on physical examination. 6. No clinically relevant abnormalities on vital signs. 7. No clinically relevant abnormalities on 12-lead EKG. 8. No clinically relevant abnormalities on laboratory tests. 9. Neg. test results on anti-HIV-1Ab and anti-HIV-2Ab, HbsAG and anti-HCVAb 10. Non-smoker or ex-smoker 11. Willingness to accept and comply with all study procedures and restrictions. 12. Female subject of a) non-child-bearing potential or b) of childbearing potential and agrees to use an accepted, highly effective contraceptive method until the end of the study. Exclusion Criteria: 1. Known hypersensitivity/allergy reaction to the study drug substance or any of the excipients. 2. Known severe hypersensitivity reaction to any other drug. 3. Any medical condition (e.g., gastrointestinal, renal or hepatic, including peptic ulcer, inflammatory bowel disease or pancreatitis) or surgical condition (e.g., cholecystectomy, gastrectomy) that may affect drug pharmacokinetics (absorption, distribution, metabolism or excretion) or subject's safety. 4. History of glucose-6-phosphate dehydrogenase deficiency. 5. History of severe hypotension or shock. 6. History of acute pulmonary edema, heart failure, coronary artery disease or myocardial infarction. 7. History of orthostatic hypotension, collapse, fainting, syncope, or vasovagal reaction. 8. History of substance or alcohol abuse within the previous 2 years. 9. Use of contact lenses. 10. SBP \<95 mmHg and/or DBP \<45 mmHg. 11. Serum transaminases alanine aminotransferase (ALT) or aspartate aminotransferase (AST) above the upper limit of the normal range. 12. Estimated renal creatinine clearance (CLCr) below the lower limit of normal range, based on creatinine clearance calculation by the Cockcroft-Gault formula and normalized to an average body surface area of 1.73 m2. 13. Positive result in drugs-of-abuse or ethanol tests. 14. Use of a depot injection or an implant of any drug (except for contraceptives) within the previous 6 months. 15. Average weekly alcohol consumption of \>14 units for males and \>7 units for females within the previous 6 m…