Tapentadol vs Tramadol in Total Knee Arthroplasty
Unknown statusPhase 4NCT06269770
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Compare the effectiveness of tapentadol and tramadol as part of a multimodal analgesia treatment for Total Knee Replacement (TKR).
Study details
- Official title
- Multimodal Analgesia in TKA. The Role of Tapentadol
- Conditions
- Total Knee Replacement
- Post-operative Pain
- Chronic Pain
- Interventions
- Sponsor
- University of Thessaly
- Start date
- 2023-05-01
- Primary completion
- 2025-05-01
- Sex
- All
- Age range
- from 18 Years to 80 Years
- Results posted
- No results posted in this snapshot
- Countries
- Greece
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Patients for elective TKR * ASA PS I - III Exclusion Criteria: * Patient refusal * Cognitive disfunction * Severe psychiatric disease * Under medication with MAO inhibitors, tricyclic antidepressants, serotonin reuptake inhibitors * Not speaking Greek * Known allergy to the study drugs * Contraindications for any of the study drugs * Chronic renal failure (GFR \< 50 ml/h) * Liver failure * Known regular use or misuse of opioids * Pregnant women * Patients undergoing general anesthesia
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06269770