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Examining the Effect of Prolotherapy on Quality of Life and Painkiller Use in Patients With Knee Pain

CompletedNot applicableNCT06345222
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

92 patients with a diagnosis of primary knee pain of unknown cause followed at the family medicine outpatient clinic and who met our exclusion criteria were invited to the study. When creating patient list, the examination of patients, interviews with patients, as well as their medical records and examinations were used. Patients were divided into two groups: prolotherapy (n=46) and control group (n=46) by simple randomization method. However, when the study started, 32 people in the prolotherapy group and 33 people in the control group of these patients participated in the study. Prior to the research, detailed information was provided about the research in the experimental and control groups and signed consent was obtained from all participants that they volunteered to participate in the research. 5% dectrose was applied to the prolotherapy group by injection method to the pain area. In the control group, existing medical treatments were continued and no injection procedure was performed. Before the research, all participants were evaluated with Case Report Form, Visual Analog Scale (VAS) and Quality of Life Scale Short Form (SF-36). The cases in the experimental and control groups were re-evaluated with the VAS and SF-36 scales at the first month.

Study details

Official title
Examining the Effect of Prolotherapy on Quality of Life and Painkiller Use in Patients With Knee Pain
Conditions
  • The Aim of This Research is to Investigate the Effect of Prolotherapy on Quality of Life and Painkiller Use in Patients With Chronic Knee Pain
Interventions
  • Procedure: Prolotherapy
Sponsor
Bursa Yuksek Ihtisas Training and Research Hospital
Start date
2023-05-01
Primary completion
2023-07-31
Sex
All
Age range
from 18 Years to 65 Years
Results posted
No results posted in this snapshot
Countries
Turkey (Türkiye)
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * patients who suffer from primary knee osteoarthritis Exclusion Criteria: * Inflammatory knee pain * Cellulitis * Septic arthritis * Local abscess * Bleeding disorders * Patient on anticoagulant medication * Patients allergic to dextrose * Diabetes Mellitus * breathing problems * Electrolyte imbalance * Kidney or liver disease

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06345222