Pain After Removal of Mandibular Third Molars With or Without Advanced Platelet-rich Fibrin
Unknown statusEarly phase 1NCT06377839
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Pain is the most common complication following surgical removal of an impacted mandibular third molar. Several risk factors may increase the intensity and duration of pain following removal of mandibular third molars. Acute postoperative pain can transcript into postoperative chronic pain without an explainable reason or a specific risk factor. The use of advanced platelet-rich fibrin in the extraction socket following surgical removal of mandibular third molar have diminished the intensity and duration of acute postoperative pain and facilitated improved wound healing. The objective of the present study is therefore to identified specific risk factors and predictors for developing postoperative chronic pain following surgical removal of mandibular third molars with or without advanced platelet-rich fibrin applied in the extraction socket using epigenetic modulation.
Study details
- Official title
- Assessment of Chronic Pain Predictors Following Surgical Removal of Mandibular Third Molars
- Conditions
- Interventions
- Biological: Advanced platelet-rich fibrin in the ekstraction socket
- Sponsor
- Aalborg University Hospital
- Collaborators
- Aalborg University
- Start date
- 2024-01-10
- Primary completion
- 2024-04-17
- Sex
- All
- Age range
- from 18 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Denmark
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Age ≥ 18 years. * Presence of a semi- or fully impacted mandibular third molar. * Indication for surgical removal of mandibular third molar. Exclusion Criteria: * Patients suffering from chronic pain syndrome. * Patients in need of daily analgetic. * Pregnancy. * Psychiatric problems or unrealistic expectations.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT06377839